Lr3-igf1

[Sledge]

Who's used LR3-IGF1?

It's recently become avaliable to me. I'd be interested in feedback on running it during and between AAS cycles.

Also results experienced and compaired to rHgh. ( I loved growth but can't get it any more)

[maxititer]

there is a lot of contradicting opinions and reports on IGF1 LR3 it's use and effect. I believe it can be used, for some plateau situation. I will PM you how.

[hilly]

max if you dont mind yould you send me that pm as well please

[maxititer]

Here we go...

Before to use IGF1 you need to reach high anabolic state. If it is not present, new cells will not receive nutrition will stop dividing and die. It is important not only stimulate growth but also know how to support it.

You can use this protocol to start, or make some modifications which will suits you. with this protocol IGF can be started from third week

Optimized adaptation protocol (lantus/deca/GH) - RX Muscle Forums


Insulin and very large amount of insulin is very important with IGF1. because IGF1 will stimulate satellite cells proliferation and those cells does not have GLUT4 transporters on membranes. It is immature cells and totally depends on insulin in ability to absorb water soluble nutrients. After injection of IGF1 demand for insulin rising in 8 times in 1-2 hours.

Few words about training it is good to have 2 training days one after another then 1-2 days rest and again 2 training days.

Now, how and when to inject

All injection done PWO.

dilute 1000mcg IGF1LR3 vial with 2ml sterile water for injection (no need AA). Take two 5 ml syringes aspirate in each syringe 0.5 ml of IGF1LR3, then aspirate 4.5ml of water. By diluting IGF1 we increasing its bio availability a lot. Now, inject it into those muscles which were trained, avoid using area close to central line of each muscle. Always inject on sides, because in central area a lot of large blood vessels and nerves.

Right after IGF is done, discharge 20iu of lantus into each of two 5 ml syringes. Again dilute it up to total amount in syringe 5 ml. Inject bilateral into same areas.

That way you are injected 40iu lantus and 500mcg of IGF1 LR3. next day repeat, it is main reason to have 2 training days one after another. Your IGF1 will not sit in refrigerator for long.


After first 2 vials are gone, you can move on and injected 1000 mcg at once. Total will be 4 mg per week.

[Tatyana]

I have recently come across someone who was saying that it is essential on reconstituting peptides in sodium chloride, I would think normal saline 0.9% NaCl.

This does make sense when you think of the charges on amino acids and peptides, it is the whole 'salting in/salting out' thing.

[maxititer]

I have recently come across someone who was saying that it is essential on reconstituting peptides in sodium chloride, I would think normal saline 0.9% NaCl.

This does make sense when you think of the charges on amino acids and peptides, it is the whole 'salting in/salting out' thing.

I dont think it is good idea, because before lyphilisation all peptides and recombinant proteins are buffered to optimal pH. Peptides usually are having acidic pH, altering it with 0.9% NaCl will be not good idea at all.

[Sledge]

Thanks mate. That was great info here and in the PM.

[maxititer]

welcome mate

to get results with peptides a bit more complicated then most people think.

no wander so many people have wasted a lot of money and they are absolutely right to say, - it did not work, but did not work for them, does not means it did not work at all.

How it is possible for IGF1 LR3 do not work, it is main growth stimulating pathway in our body. Also IGF1 LR3 posses 10 time more ability to bind to IGF1 receptor then normal IGF1.

I do not sale IGF1 and do not have ill earned wealth expectations while writing it.

[Tatyana]

welcome mate

to get results with peptides a bit more complicated then most people think.

no wander so many people have wasted a lot of money and they are absolutely right to say, - it did not work, but did not work for them, does not means it did not work at all.

How it is possible for IGF1 LR3 do not work, it is main growth stimulating pathway in our body. Also IGF1 LR3 posses 10 time more ability to bind to IGF1 receptor then normal IGF1.

I do not sale IGF1 and do not have ill earned wealth expectations while writing it.

I think some of this is related to the quality of the peptide.

[heavymetal64]

I used IGF LR3 right after a show and got INCREDIBLE results. Stayed lean as hell also.

Make sure to use it properly, and there's really no need to take your dosage too high too fast. I hear of guys injecting 200mcg PWO. That's just a waste of money. Be sure to have carbohydrates on hand and meal timing down perfectly - just as if you were taking insulin.

Let me know if you have any questions as far as mixing, site injections, etc.

[hilly]

I used IGF LR3 right after a show and got INCREDIBLE results. Stayed lean as hell also.

Make sure to use it properly, and there's really no need to take your dosage too high too fast. I hear of guys injecting 200mcg PWO. That's just a waste of money. Be sure to have carbohydrates on hand and meal timing down perfectly - just as if you were taking insulin.

Let me know if you have any questions as far as mixing, site injections, etc.

what dose did you use mate and did you shoot it pwo. i have 1mg sat in my freezer and cnt decide wether i have another to run it or need more?

[saiyajinali]

I got really good results on only dosing 40mcg at a time.. And I did only run it 4 times a week. 2 days on 1 day off, & 2 days on again.. My AAS levels were pretty low too.. I liked it ALLOT..

[hilly]

I got really good results on only dosing 40mcg at a time.. And I did only run it 4 times a week. 2 days on 1 day off, & 2 days on again.. My AAS levels were pretty low too.. I liked it ALLOT..


how were you shooting it mate pre workout or post or during the day and was it subq or IM

[saiyajinali]

how were you shooting it mate pre workout or post or during the day and was it subq or IM
post workout.. IM In my bi's that I am trying to bring up. I actually could tell a difference...

[heavymetal64]

what dose did you use mate and did you shoot it pwo. i have 1mg sat in my freezer and cnt decide wether i have another to run it or need more?


You can make it work for a four week cycle with only 1mg. No need to break this first time out. Honestly, I started at 10mcg and worked my way upto 50mcg PWO. I got good results off of those and don't really see the need to go above this. Supposedly there's site enhancement effects off of IGF but these weren't noticable enough for daily bi lateral injections. I only injected on training days and never broke 50mcg for a four week cycle. If you've got good stuff, you'll get good results. Make sure to mix correctly and SLOWLY. This stuff is fragile as hell.

[firefightermac]

Here we go...

Before to use IGF1 you need to reach high anabolic state. If it is not present, new cells will not receive nutrition will stop dividing and die. It is important not only stimulate growth but also know how to support it.

You can use this protocol to start, or make some modifications which will suits you. with this protocol IGF can be started from third week

Optimized adaptation protocol (lantus/deca/GH) - RX Muscle Forums (http://forums.rxmuscle.com/showthread.php?t=10697)


Insulin and very large amount of insulin is very important with IGF1. because IGF1 will stimulate satellite cells proliferation and those cells does not have GLUT4 transporters on membranes. It is immature cells and totally depends on insulin in ability to absorb water soluble nutrients. After injection of IGF1 demand for insulin rising in 8 times in 1-2 hours.

Few words about training it is good to have 2 training days one after another then 1-2 days rest and again 2 training days.

Now, how and when to inject

All injection done PWO.

dilute 1000mcg IGF1LR3 vial with 2ml sterile water for injection (no need AA). Take two 5 ml syringes aspirate in each syringe 0.5 ml of IGF1LR3, then aspirate 4.5ml of water. By diluting IGF1 we increasing its bio availability a lot. Now, inject it into those muscles which were trained, avoid using area close to central line of each muscle. Always inject on sides, because in central area a lot of large blood vessels and nerves.

Right after IGF is done, discharge 20iu of lantus into each of two 5 ml syringes. Again dilute it up to total amount in syringe 5 ml. Inject bilateral into same areas.

That way you are injected 40iu lantus and 500mcg of IGF1 LR3. next day repeat, it is main reason to have 2 training days one after another. Your IGF1 will not sit in refrigerator for long.


After first 2 vials are gone, you can move on and injected 1000 mcg at once. Total will be 4 mg per week.
sounds expensive!

for how long would you run it this way?

would it be sufficient to do this for say a two week "blast" would that stimulate sufficient new muscle cell growth?

[firefightermac]

You can make it work for a four week cycle with only 1mg. No need to break this first time out. Honestly, I started at 10mcg and worked my way upto 50mcg PWO. I got good results off of those and don't really see the need to go above this. Supposedly there's site enhancement effects off of IGF but these weren't noticable enough for daily bi lateral injections. I only injected on training days and never broke 50mcg for a four week cycle. If you've got good stuff, you'll get good results. Make sure to mix correctly and SLOWLY. This stuff is fragile as hell.

wasnt max just saying you need 1mg per day? your saying 1mg per month! thats quite a dosage difference...

[maxititer]

sounds expensive!

for how long would you run it this way?

would it be sufficient to do this for say a two week "blast" would that stimulate sufficient new muscle cell growth?

IGF1 LR3 is quite expensive you are right. You can try instead Increlex which is recombinant IGf1 and coming in 40 mg vial and an average wholesale price per vial is $560, $14 per MG not bad if you only can get it

This kind of IGF1 not so well known in bodybuilding, but in other sports used quit a lot and doses 6-9 mg per day.

IGF1 in our body (in most tissues) presented in very large quantities, it is most common peptide and only in blood we are having 6-7 mg of IGF1 at any moment.

Personally, I will not take seriously any evidence of "tremendous growth" after 50-100 mcg of IGF1 LR3.

[firefightermac]

Thanks Max. What about the other qns? How long would you run it this way and would it be sufficient to "blast" it in this way?

On another note I read recently there was a scare on the 29/06 about the link between cancer and Lantus. What do you make of this since you are a strong believer of the Lantus insulin?

[maxititer]

Thanks Max. What about the other qns? How long would you run it this way and would it be sufficient to "blast" it in this way?

take a look at the protocol and run from week 3 up to week 8 so it is 6 weeks



On another note I read recently there was a scare on the 29/06 about the link between cancer and Lantus. What do you make of this since you are a strong believer of the Lantus insulin?

I did not heard anything about it. If you are concerned then use levemir, levemir did not act on IGF1 receptor.

[firefightermac]

I suppose it wouldnt make a difference if you are going to inject 1mg of IGF anyway. Do you feel that massive amounts of IGF would cause cancers? there is massive debate about this. What is your take on it max?

[maxititer]

cancer cells contains some genetic mutations ,as result cancer cells unable to differentiate and become functional somatic cell. IGF1 cannot cause such mutation and cannot cause cancer in first instance.


IGF1 will cause both proliferation and differentiation of cells which are expressing IGF1 receptors. Cancer cells also can express IGF1 receptors, as it is major growth pathway for all undifferentiated/dividing cells in our body.

Conclusion is that IGF1 will not cause cancer but can stimulate proliferation of existed clones of cancerous cells.

How much such stimulation can be significant in case of IGF1 LR3 - nil.

that question of IGF1LR3 safety was discussed in this review

http://a16.in/files/NZGP_LR3_SafetyReview.pdf

[firefightermac]

Interesting. So even 1000mcg shots of IGF would pose little threat since its out in 20 mins and they say that levels need to be raised for long times at more than 50%.

Would this in your opinion mean that long acting insulin, ghrp6, grf, cjc etc pose a cancer threat since they will elevate circulating IGF substantially and for extended periods of time?

[maxititer]

Interesting. So even 1000mcg shots of IGF would pose little threat since its out in 20 mins and they say that levels need to be raised for long times at more than 50%.

Would this in your opinion mean that long acting insulin, ghrp6, grf, cjc etc pose a cancer threat since they will elevate circulating IGF substantially and for extended periods of time?

non of them can create cancerous cells. that is important to understand first of all. Those peptides are bio identical peptides. For example liver producing a lot of IGF1 everyday, does it means that liver producing carcinogen, not.

but that also depend a lot on what you want to hear at that moment.

[firefightermac]

What I want to hear at what moment? I just want your opinion.