View Full Version : Methyl-D~Methyldienolone

01-09-2010, 11:05 AM
Methyl-D (Methyldienolone)

Androgenic 200-300
Anabolic 1,000
Standard Methyltestosterone (oral)
Chemical Name 17a-methyl-17beta-hydroxyestra4,9(10)dien-3-one
Estrogenic Activity none
Progestational Activity moderate

Methyldienolone is an anabolic steroid that was researched in the early 1960's, but never sold as a prescription drug. It is a nandrolone-based compound, modified to be orally active and to have greatly increased anabolic properties. Methyldienolone is a close chemical cousin of methyltrienolone, one of the strongest steroids profiled in this reference. Methyldienolone is not quite as potent, however it remains quite strong next to most commercial agents. Animal tests find it to be 5 times more potent than Dianabol, 10 times more potent than methyltestosterone, and 13 times more potent than Primobolan® on a milligram for milligram basis. Although the real world relevance of these values may be questionable, methyldienolone is well favored by bodybuilders for its ability to promote lean muscle gains with minimal side effects.

Methyldienolone was first described in 1960.623 Eli Lilly & Co. (U.S.) developed this steroid, although the firm never released it as an actual medicine. It is of note that Lilly also developed a 17-alpha-ethylated version (ethyldienolone) at the same time, which had an even more favorable anabolic to androgenic ratio in standard assay tests, but was not quite as potent overall. Being that methyldienolone was never sold as a prescription drug, it remained a research steroid of little interest for approximately forty years. The steroid actually came to life not as a prescription agent, but as an OTC "nutritional supplement" in 2004. Bruce Kneller, who had found the old research on methyldienolone and determined it to be a favorable agent to market with Gaspari Nutrition, was actually credited with developing the product. Gaspari sold the agent for a brief time as Methyl-D, before the 2004 amended Anabolic Steroid Control Act was passed, eliminating much of the grey area "prohormone" or "prosteroid" market in the U.S. Today, methyldienolone is again unavailable to athletes.

How Supplied:
Methyldienolone is not available as a commercial agent. When sold as a nutritional supplement, it contained 1mg of steroid per tablet.

Structural Characteristics:
Methyldienolone is a modified form of nandrolone. It differs by: 1) the addition of a methyl group at carbon 17alpha to protect the hormone during oral administration and 2) the introduction of a double bond at carbon 9, which increases its binding affinity and slows its metabolism. The resulting steroid is significantly more potent than its nandrolone base, and displays a much longer half-life and lower affinity for serum-binding proteins in comparison.

Administration (General):
Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract. For maximum utilization, this steroid should be taken on an empty stomach.
Administration (Men):
Methyldienolone was never approved for use in humans. Prescribing guidelines are unavailable. Effective oral daily doses for physique-or performance-enhancing purposes fall in the range of 2~10 mg. At this level, one should expect measurable strength and lean tissue gains, which should be accompanied by decent fat loss and, minimal side effects. In an effort to reduce liver strain, it is usually recommended to limit drug d'uration to no longer than 68 weeks, after which point a break is taken from all c-17 alkylated steroids. Users often avoid combining this drug with other liver toxic orals, and instead opt to use an injectable base when stacking. A dose of 5 mg per day of methyldienolone combined with 400 mg weekly of testosterone cypionate/enanthate or Equipoise® seems to be a common and effective lean-mass stack. Trenbolone (225 mg) or Primobolan® (300-400 mg) is often used instead for cutting purposes.
Administration (Women):
Methyldienolone was never approved for use in humans. Prescribing guidelines are unavailable. This agent is not recommended for women for physique-or performanceenhancing purposes due to its high level of potency and tendency to produce virilizing side effects. Note that the high anabolic to androgenic ratio of methyldienolone makes use possible without significant virilization, but would likely require measuring very small doses (well below 1mg per day) and respecting a very periodic use schedule (4 weeks or less).

Llewellyn’s W. (2009). Anabolics (9th ed), Methyl-D Methyldienolone(pp. 302-304): Jupiter, FL: Molecular Nutrition

02-10-2010, 03:54 PM
can you still get this stuff?????

03-09-2012, 05:57 PM
It is now available as an otc supplement in UK,tempted it to try it.Has anyone here have experience with this compound?