View Full Version : anabolic steroid-induced cardiomyopathy and acute liver failure

04-13-2010, 08:50 PM
interesting case report.

cardiovascular disease and hepatic toxicity should always be of concern for those with history of chronic aas usage.

the following is the link for the full article. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699014/

World J Gastroenterol. (http://javascript<b></b>:AL_get(this, 'jour', 'World J Gastroenterol.');) 2009 Jun 21;15(23):2920-2.
Anabolic steroid-induced cardiomyopathy underlying acute liver failure in a young bodybuilder.

Bispo M (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Bispo%20M%22%5BAuthor%5D), Valente A (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Valente%20A%22%5BAuthor%5D), Maldonado R (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Maldonado%20R%22%5BAuthor%5D), Palma R (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Palma%20R%22%5BAuthor%5D), Glória H (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Gl%C3%B3ria%20H%22%5BAuthor%5D), Nóbrega J (http://www.ncbi.nlm.nih.gov/pubmed?term=%22N%C3%B3brega%20J%22%5BAuthor%5D), Alexandrino P (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Alexandrino%20P%22%5BAuthor%5D).
Department of Gastroenterology, Egas Moniz Hospital, Lisbon, Portugal. [email protected]

Heart failure may lead to subclinical circulatory disturbances and remain an unrecognized cause of ischemic liver injury. We present the case of a previously healthy 40-year-old bodybuilder, referred to our Intensive-Care Unit of Hepatology for treatment of severe acute liver failure, with the suspicion of toxic hepatitis associated with anabolic steroid abuse. Despite the absence of symptoms and signs of congestive heart failure at admission, an anabolic steroid-induced dilated cardiomyopathy with a large thrombus in both ventricles was found to be the underlying cause of the liver injury. Treatment for the initially unrecognized heart failure rapidly restored liver function to normal. To our knowledge, this is the first reported case of severe acute liver failure due to an unrecognized anabolic steroid-induced cardiomyopathy. Awareness of this unique presentation will allow for prompt treatment of this potentially fatal cause of liver failure.

04-13-2010, 09:38 PM
Good post!