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HammerStrength12
10-21-2010, 10:47 AM
All (esplendido especially)

It seems like in this forum, nolvadex is usually suggested as the SERM of choice for HPTA restoration after a cycle. Just curious as to why. Does it have anything to do with leydig cell function and responsiveness to LH once PCT is over? Thanks for the help.

Bobr
10-22-2010, 09:30 AM
All (esplendido especially)

It seems like in this forum, nolvadex is usually suggested as the SERM of choice for HPTA restoration after a cycle. Just curious as to why. Does it have anything to do with leydig cell function and responsiveness to LH once PCT is over? Thanks for the help.


Bump. Good question.

esplendido
10-23-2010, 01:48 AM
All (esplendido especially)

It seems like in this forum, nolvadex is usually suggested as the SERM of choice for HPTA restoration after a cycle. Just curious as to why. Does it have anything to do with leydig cell function and responsiveness to LH once PCT is over? Thanks for the help.

Nolvadex also competes with estrogen receptors on the hypothalamus, fooling it into believing there's a shortage of estrogen. In response, it cycles out LH and FSH to create more testosterone to induce aromatization to bring up estrogen levels. Of course, besides kicking the HPTA feedback loop into a restarted cycle (which will cause more estrogen) it protects the mammary glands from gyno with the elevated levels. One could, or perhaps should use aromasin as well to keep estrogen down, even though nolva is protecting you from the most unsavory sides of high estrogen.

A typical PCT protocol would be (daily by week) nolva at 40-40-20-20, and if aromasin is used, (again daily by week) 25-15-10-5

HCG is absolutely unnecessary.