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Thread: New ephedrine HCL study
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02-05-2013, 10:07 AM #1
New ephedrine HCL study
For those who havent seen it on the other board..
http://www.ncbi.nlm.nih.gov/pubmed/23064293
This latest piece of research published on Diabetologia details the brown adipose tissue activation taking place after acute oral administration of ephedrine on lean human subjects. Obese subjects seem not to response as such, but that's not a bad thing per se as the positive effects of chronic ephedrine administration on obese subjects have been well reported (http://www.ncbi.nlm.nih.gov/pubmed/4014068, http://www.ncbi.nlm.nih.gov/pubmed/8124407). Ephedrine seems to become more effective the longer one takes it, suggesting actual beta-adrenergic receptor sensitization. This should serve to discredit people among the establishment who have been suggesting that Ephedrine should be cycled in order to keep receptor sensitivity high, like one should do with compounds highly effective acutely, like Clenbuterol.
Overall, I believe that the benefits of ingesting ephedrine, especially along with a xanthine (caffeine), are just too evident to pass up at this point, even for the common Joe. Bodybuilders should find it especially beneficial, considering it also serves as a muscle-sparing anti-catabolic agent in times of reduced calorie intake (http://www.ncbi.nlm.nih.gov/pubmed/1310922, http://www.ncbi.nlm.nih.gov/pubmed/8384179). It also seems that the more muscle present, the more efficient Ephedrine becomes at burning fat, suggesting a synergistic effect (http://www.ncbi.nlm.nih.gov/pubmed/3922230).
As for any potential dangers ephedrine consumption may yield, even at slightly supratherapeutic doses, research seems to suggest there are none. Yes, that is correct. Aside from the initial side effects that ALWAYS seem to decline (see: blood pressure- http://www.ncbi.nlm.nih.gov/pubmed/8148931), there seem to be no dangers to chronic ephedrine use. It is no secret (well, it might be to some who tend to believe that any banned drug has been banned for a good reason) that scientists have been suggesting for decades that ephedrine can be used as an EFFECTIVE long-term treatment for obesity (http://www.ncbi.nlm.nih.gov/pubmed/8384172, http://www.ncbi.nlm.nih.gov/pubmed/8384185).
My personal opinion- if there is only one drug you could be using as a bodybuilder at supratherapeutic doses, that should be Ephedrine. The risk to reward ratio of this compound is simply better than any other drug's (always according to research)- including AAS, which I'm an advocate of.
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02-05-2013, 10:18 AM #2
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02-05-2013, 10:36 AM #3
Ahh. Takes me back to the 80's 90's ECA days of the very popular pre WO dose of Broncaid (Eph), asprin and chased down with coffee. Every time I tried it I got an irregular heartbeat. Oh well. When Broncaid and its equivs were taken off the shelf I never knew whether it was because of the Gov position on ECAs or the fact that Broncaid like Sudafed can be tweeked into Meth.
Yes it was/is muscle sparing/fat burning while reducing calories.
BaldieMY MIND & BODY ARE AT ONE WITH MY POWER & STRENGTH............JM
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02-05-2013, 10:40 AM #4
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02-05-2013, 11:03 AM #5
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I haven't done an ECA stack in years.... Might be time to incorporate it again
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02-05-2013, 11:06 AM #6
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02-05-2013, 11:07 AM #7
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02-05-2013, 11:07 AM #8
I think some states in the US still allow purchase of ephedrine hcl in doses of less than 12.5mg a tab
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02-05-2013, 11:08 AM #9
problem with bronkaid is coughing up shit while working out is annoying
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02-05-2013, 11:36 AM #10
I can walk into any CVS in PA and get Bronkaid at 25mg/tab.
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02-05-2013, 11:40 AM #11
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02-05-2013, 12:49 PM #12
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02-05-2013, 01:40 PM #13
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Sorry to crash the party, but I just read the article. They were using a dosage (single pill at one time, keep in mind) of 2.5 mg/kg.....for me (88 kg) that is over 200mg of ephedrine hcl in a single dose. NO RESULTS (no brown adipose tissue activation) was seen at a dosage of 1 mg/kg (still ~90 mg of ephedrine hcl for your average male). I don't know about y'all but I'm not looking to take 200 mg of ephedrine HCl in the mornings.
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02-05-2013, 02:14 PM #14
Just got 12 bottles of Ephedrine HCL...It's still OTC here (in 8mg) and pretty cheap, you can get 50 pills for 4 bucks.
ECA always worked well for me, I try to bring in breaks when I can though so I don't get worn out, I guess adrenal fatigue.
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02-05-2013, 02:38 PM #15
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