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  1. #1
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    Default HRT and Building Tolerance

    Do people who are on HRT for years (5, 10, 20+years) gain a tolerance to the dosing?

    What I mean is: If someone is on 150mgs of Test and their levels are in the 900 range, would that decrease over time where they would need to up their dose to 200mgs or more to keep their range in the 900 range? (these are just hypothetical numbers for this example).

    Thank you!

  2. #2
    OLYMPIAN s2h's Avatar
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    Tolerance is not a issue with TRT...what does happen as men age is they aromatize testosterone to estrogen by a increase in the aromatase enzyme....it occurs in all men...so when a male feels their 150mg ew is losing its punch....estrogen is the #1 culprit and needs to be addressed...

  3. #3
    OLYMPIAN s2h's Avatar
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    I have been on prescribed trt for 14-15 years now...and AI adjustments have been needed at times..

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    Just stopping by to say hi to S2h! Hope all is well with U!
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  5. #5
    RX MEMBER scottt's Avatar
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    Lets say I was on hrt 200mg test Cyp every 6 days what would be a good dosage of exemestane?

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    Cartman's body double bad rad's Avatar
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    Quote Originally Posted by scottt View Post
    Lets say I was on hrt 200mg test Cyp every 6 days what would be a good dosage of exemestane?
    I would start with 12.5mg 3x weekly and adjust from there. Dosing is very individual and takes some time to dial in.
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  7. #7
    RX MEMBER scottt's Avatar
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    Thanks

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    That is exactly what I wanted to know, thank you!

    Quote Originally Posted by s2h View Post
    I have been on prescribed trt for 14-15 years now...and AI adjustments have been needed at times..

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    I've been on 200 mg weekly for about ten years and my levels are pretty consistent. My doctor cuts me down to 100mg for a month or so once in a blue moon.

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    Also prescribes arimidex to use every so often, might have used it a total of 3x for a week in the ten years I've been on hrt. Hope this helps ?

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    That's great, thank you for the info!

    Quote Originally Posted by supbro! View Post
    I've been on 200 mg weekly for about ten years and my levels are pretty consistent. My doctor cuts me down to 100mg for a month or so once in a blue moon.

  12. #12
    OLYMPIAN s2h's Avatar
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    Quote Originally Posted by Hoss06 View Post
    Just stopping by to say hi to S2h! Hope all is well with U!
    All good Hoss....poke my head in every so often..you been good?

  13. #13
    OLYMPIAN s2h's Avatar
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    Quote Originally Posted by scottt View Post
    Lets say I was on hrt 200mg test Cyp every 6 days what would be a good dosage of exemestane?
    You would need to get labs to find out for sure...25mg day after injection and 12.5mg eod after that would be a good starting point...

  14. #14
    OLYMPIAN s2h's Avatar
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    Almost all DR's in the US prescribe adex...some recent research shows adex has the potential to be worse for your hdl/ldl ratio then testosterone..it has reflected that in my labs also...I use aromasin whenever possible...

  15. #15
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    I've been on over 10 year I believe
    140mg put me at 28 (4-32) just got reteste and it was 14
    So I want to say yes
    I just got a retest so will know For sure as last time not sure when last injection was. Want overly consisten


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