Results 1 to 5 of 5
  1. #1
    RX MEMBER
    Join Date
    May 2010
    Posts
    28
    Rep Power
    0

    Post Gyno treatment with Kybella (deoxycholic acid)

    Was wondering if this could work on gyno reduction. If it dissolves fat the why is it only approved for the fat under the chin area? It sounds to me like it could be very promising and the patient wouldnt require surgery.

    Thoughts??

    The U.S. Food and Drug Administration today approved Kybella (deoxycholic acid), a treatment for adults with moderate-to-severe fat below the chin, known as submental fat. Using Kybella for the treatment of fat outside of the submental area is not approved and is not recommended.
    Kybella is identical to the deoxycholic acid that is produced in the body. Deoxycholic acid produced in the body helps the body absorb fats. Kybella is a cytolytic drug, which when injected into tissue physically destroys the cell membrane. When properly injected into submental fat, the drug destroys fat cells; however, it can also destroy other types of cells, such as skin cells, if it is inadvertently injected into the skin.
    “Treatment with Kybella should only be provided by a licensed health care professional, and patients should fully understand the risks associated with use of the drug before considering treatment,” said Amy G. Egan, M.D., M.P.H., deputy director of the Office of Drug Evaluation III in the FDA’s Center for Drug Evaluation and Research. “It is important to remember that Kybella is only approved for the treatment of fat occurring below the chin, and it is not known if Kybella is safe or effective for treatment outside of this area.”
    Kybella is administered as an injection into the fat tissue in the submental area. Patients may receive up to 50 injections in a single treatment, with up to six single treatments administered no less than one month apart. Kybella is being provided in single patient use vials and should not be diluted or mixed with any other compounds.
    The safety and effectiveness of Kybella for treatment of submental fat were established in two clinical trials which enrolled 1,022 adult participants with moderate or severe submental fat. Participants were randomly assigned to receive Kybella or a placebo for up to six treatments. The results showed that reductions in submental fat were observed more frequently in participants who received Kybella versus placebo.
    Kybella can cause serious side effects, including nerve injury in the jaw that can cause an uneven smile or facial muscle weakness, and trouble swallowing. The most common side effects of Kybella include swelling, bruising, pain, numbness, redness and areas of hardness in the treatment area.
    Kybella should not be used outside of the submental area, and it should not be used if there is an infection at the injection site. Caution should also be used in patients who have had prior surgical or aesthetic treatment of the submental area.
    Kybella is being distributed in a dispensing pack that has a unique hologram on the vial label. If there is no hologram, do not use the product.

    Consumers and health care professionals are encouraged to report adverse reactions from the use of Kybella to the FDA’s MedWatch Adverse Event Reporting program at www.fda.gov/MedWatch or by calling 800-FDA-1088.
    Kybella is manufactured by Kythera Biopharmaceuticals Inc. based in Westlake Village, California.
    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

  2. #2
    Managing Dir., Rx Muscle Forums Curt James's Avatar
    Join Date
    Feb 2009
    Location
    Big Jeff's Family Restaurant, 815 Fremont Ave, South Pasadena, CA
    Posts
    49,332
    Rep Power
    2149235

    Default

    Gyno is not fat, though, right? It's glandular tissue? I'm not Dr. Blau, but...
    Facebook | Instagram | Twitter | Join Rx Muscle on Facebook!

    Contact [email protected] to be interviewed or to advertise!

  3. #3
    Managing Dir., Rx Muscle Forums Curt James's Avatar
    Join Date
    Feb 2009
    Location
    Big Jeff's Family Restaurant, 815 Fremont Ave, South Pasadena, CA
    Posts
    49,332
    Rep Power
    2149235

    Default

    Quote Originally Posted by musclesearch View Post
    When properly injected into submental fat, the drug destroys fat cells; however, it can also destroy other types of cells, such as skin cells, if it is inadvertently injected into the skin.
    Yikes.

    Great to destroy fat cells, but I'll pass on the other.
    Facebook | Instagram | Twitter | Join Rx Muscle on Facebook!

    Contact [email protected] to be interviewed or to advertise!

  4. #4
    RX MEMBER
    Join Date
    May 2010
    Posts
    28
    Rep Power
    0

    Default

    Quote Originally Posted by Curt James View Post
    Gyno is not fat, though, right? It's glandular tissue? I'm not Dr. Blau, but...
    Thanks for reply Curt!

    Isn't there different stages of gyno? The gland formation being the worst right? Most people just have the fatty breast tissue build up which in theory this could permenantly destroy. I have a couple friends that have had it since puberty. Also I'm still curious if it would destroy the gland as well though. I mean it says it can destroy skin and even muscle if administered incorrectly. Yes it def has some drawbacks but this could be alternative to surgery. Especially if you only have a small amount but are still self conscious about it.

  5. #5
    RX MEMBER
    Join Date
    Nov 2017
    Posts
    2
    Rep Power
    0

    Default

    I’m very interested in this question and have thought the same thing. I carry most of my body fat on my pecs and armpits. I don’t think anyone would say I have gyno but it causes me to have a lack of definition there while I have a 6 pack. I sit around 10% bf. I think if I got lower it would help but if an injjectable could get me the desired effect that would be worth the $1000 or so that I estimate it would cost.

    To the the original question I have seen off label uses of Kybella on YouTube videos so I think you can find a doc who will do it. But I think you are asking if it has been done and what we’re the results. I’d like to know the same.

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •