Results 1 to 2 of 2

Thread: Diet Soda

  1. #1
    OLYMPIAN Joshua H's Avatar
    Join Date
    Feb 2009
    St. Louis
    Rep Power

    Thumbs up Diet Soda

    Ingestion of Diet Soda Before a Glucose Load Augments Glucagon-Like Peptide-1 Secretion

    Rebecca J. Brown, MD, Mary Walter, PHD and Kristina I. Rother, MD, MHSC
    + Author Affiliations

    From the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
    Corresponding author: Rebecca J. Brown, [email protected].

    OBJECTIVE The goal of this study was to determine the effect of artificial sweeteners on glucose, insulin, and glucagon-like peptide (GLP)-1 in humans.

    RESEARCH DESIGN AND METHODS For this study, 22 healthy volunteers (mean age 18.5 ± 4.2 years) underwent two 75-g oral glucose tolerance tests with frequent measurements of glucose, insulin, and GLP-1 for 180 min. Subjects drank 240 ml of diet soda or carbonated water, in randomized order, 10 min prior to the glucose load.

    RESULTS Glucose excursions were similar after ingestion of carbonated water and diet soda. Serum insulin levels tended to be higher after diet soda, without statistical significance. GLP-1 peak and area under the curve (AUC) were significantly higher with diet soda (AUC 24.0 ± 15.2 pmol/l per 180 min) versus carbonated water (AUC 16.2 ± 9.0 pmol/l per 180 min; P = 0.003).

    CONCLUSIONS Artificial sweeteners synergize with glucose to enhance GLP-1 release in humans. This increase in GLP-1 secretion may be mediated via stimulation of sweet-taste receptors on L-cells by artificial sweetener.
    UNBA Mens Physique, USAPL 93kg,
    Blueprint for Athletes Rep, Dymatize Rep,
    Twitter & Instagram: musclesNmorsels,

  2. #2
    NOVICE JDM's Avatar
    Join Date
    Apr 2009
    West Palm Beach, fl.
    Rep Power


    Interesting, i drink diet soda all the time.

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts