Peptides and women??

[tankygirl]

I might suggest to you to use less of the modified GRF 1-29(CJC) next time and switch to ipamorelin. The GHRP6 increases ghrelin levels. Why is that an issue? Well ghrelin is a hormone produced mainly the human stomach and epsilon cells of the pancreas. Any increase in ghrelin production is what stimulates hunger. Since GHRP-2, GHRP-2, and hexarelin all increase ghrelin production most of us are going to have hunger issues. Ipamorelin does not stimulate ghrelin production so you won't have the huger you would with the GHRP's.

Thanx for the advice, will try Ipamorelin net time. I am interested in the estrogen effect you mention... I am post menopausal and on Anavar and winnie at present... so would I even have the estrogen levels that may effect the doseage?

[BiggTexx]

I love science! thanks for posting these.

the one thing to take away from this is that the women were studied who were taking exogenic estrogen. not the other way around. but, i stand corrected about them being two different systems. obviously at some level there is an interaction.

Bryan, the 1st study does not mention oral estrogen at all. I plainly states, "GH plays a pivotal role in regulating body growth and development, which is modulated by sex steroids. A close interplay between estrogen and GH leads to attainment of genderspecific body composition during puberty. The physiological basis of the interaction is not well understood. Most previous studies have focused on the effects of estrogen on GH secretion. There is also strong evidence that estrogen modulates GH action independent of secretion."

In short, the benefits males see with GH in keeping BF levels down, women do not benefit. Because of the actions of estrogen, women have more "genderspecific" BF levels. This is also true for people who are obese. There is plent more research on this when I get back from the gym I will post it.

Now why does GHRP work better in females? It is now known that GHRP's are distinct from GHRH and do not act at the GHRH receptor, but instead act at the growth hormone secretagogue receptor, now renamed as the ghrelin receptor. So GHRP's work totally different that GHRH's because to the route they take. Estrogen does not interfere with the action of GHRP's like it does GHRH and GH.

Some more anecdotal proof of this is the almost 3 year journey my wife and I have taken using the same peptides. I have gotten HUGE results while my wife's are very modest. Yes peptides/GH work with women, but not nearly to the extent as men. GHRP's are much more effective when combines with smaller doses of GHRH's. GH/peptides is much more effective iin women with low estrogen, low bodyfat, or postmenopausal. High levels of estrogen (men or women) can slow or completely negate the BENEFITS of GH or GH pulses.

Over the past 3 years I have done extensive research combined with a couple of others and put together a whole lot of great information, especially when it come to women and the use of peptides.

[BiggTexx]

Thanx for the advice, will try Ipamorelin net time. I am interested in the estrogen effect you mention... I am post menopausal and on Anavar and winnie at present... so would I even have the estrogen levels that may effect the doseage?

Only if you are presently having your menstrual cycle. If you have amenorrhea you have not enough estrogen being produced to induce your regular menstrual cycle. Do anabolic steroids cause amenorrhea? Absolutely. As do competitive bodyfat levels. When you start breaking that ceiling of 12% essential bodyfat you also chance going into amenorrhea. With any competitive figure, fitness or BB female that 12% mark is a must.

Now if you are still having your normal menstrual cycle cycle, peptides will work but you need to concentrate more on dosing with GHRP's in combination with smaller doses of GHRH. Ipamorelin is a good choice for anyone tryigt to cut calories because it doesn't have an effect on ghrelin causing hunger. However, it still works in a similar method as GHRP's.

As for dosing, the saturation level for peptides is about 1mcg/kg/bw. I would stick to that dose for ipamorelin and got about .5mcg/kg/bw on the GHRH. The other benefit of ipamorelin is it doesn't seem to increase cortisol and prolactin levels.

[LookImDancinCrazy!]

none of you guys have yet to check my peptide thread in this forum?