Periodization vs. Variety

[Jordan Coburn]

I'd like to pose a question to the rest of you and get your feedback:

PREMISE: One wants to incorporate a holistic style of training, meaning that heavy (<8rep), moderate (say 8-12reps) and "light" (12-15 and upward) weights are incorporated, to bring about the respective adaptations afforded by stimuli and stress of those different kinds of loading...

For those that have taken this "holistic appraoch" have you compared:

1.) Different rep ranges on different days, e.g., Heavy days and Light days

vs.

2.) Different rep ranges on the SAME days

vs.

3.) Periodizing rep range approaches, e.g., in a typical "hypertrophy / strength / power" type of progression?...

If so, what has been more effective?...

SECONDARY QUESTION: Just as there is known to be interference with hypertrophy from endurance exercise, would you have concern that employing different rep ranges could dampen the overall growth response?... Or would it perhaps enhance it? Similarly, which apporach have you found most effective in avoiding injuries?

[RichDC2]

I have been told by a few pro's that no different method is better than others, as long as you stress the muscle as hard as you can. Muscle growth is an adaptation to stress. For me whenever I go lighter (15+ rep range) I can honestly say I'm not growing. I'am not pushing my strength when going lighter. I still have to switch it up for injuries. Meaning if I'm hurting I go lighter. I believe in always pushing your strength you have to grow as long as diet, supps are working too. KISS principles always apply.

[TheRage93]

Periodization or progressive overload training seems to have a higher injury rate in naturals.
Beung a Powerlifter, I've learned every method works.