Joe D CJC 1295 Dac Trial Run

[joe d]

First some basic info. I am on Hrt and part of it should be hgh. my best gh test score lately has been <0.1 on a scale ranging from 0.0-6.0.

Thanks to Gary at Osta Gain http://osta-gain.com/peptides
i have 2 free 2mg vials of cjc1295 dac to try.

my plan is to run .5mg 2x per week. if and when i feel it is working i will order more, play with dosage, and get bloods to confirm its effectiveness.

i am looking for a slight improvement in recovery, a better overall feeling, and to shed this extra fat i have put on a little easier.

all comments, tips, insight, questions, and fu's welcome.

[joe d]

Today march 5th i mixed my first vial and took my first dose of .5mg.

when mixing i noticed the stuff dissolved crystal clear within seconds.

soon after inject i noticed my face got a little flush but before i got out my glucose meter it went away blood sugar has been fine. (im diabetic and eat very little carbs as a treatment)

[GaryGranaas]

Welcome welcome!! Thank you for the journal and experiment log.

First some basic info. I am on Hrt and part of it should be hgh. my best gh test score lately has been <0.1 on a scale ranging from 0.0-6.0.

Thanks to Gary at Osta Gain http://osta-gain.com/peptides
i have 2 free 2mg vials of cjc1295 dac to try.

my plan is to run .5mg 2x per week. if and when i feel it is working i will order more, play with dosage, and get bloods to confirm its effectiveness.

i am looking for a slight improvement in recovery, a better overall feeling, and to shed this extra fat i have put on a little easier.

all comments, tips, insight, questions, and fu's welcome.

[txhawkeyes]

I have run a few weeks on 1295 WITH Dac, 1295 WITHOUT Dac, and now on 1293...couldn't pass up the 1293 price. All that time, was also running GHRP 6. Doing 100 mcg 3 x day. I noticed that I retained water a little more, and looked a little bigger when using WITH Dac. But now, on 1293, it seems to be working even better as far as the size.

Your dose of .5 mg twice a week seems logical for the 1295 WITH Dac. I have read several places that the optimum dose of that when you are doing GHRP along with it, is 2.1 mg per week...which could be done .7 - 3xweek. But I can't tell you if the 2.1 came from just adding up 100 mcg 3x day times 7 days or not.

I look forward to reading more from your log. Thanks!

[ritch]

you really should add ghrp-2 to this. 100mcg, 3 times a day. Stuff is super cheap as well.

[joe d]

you really should add ghrp-2 to this. 100mcg, 3 times a day. Stuff is super cheap as well.

if this doesnt work for me adding ghrp wont either. i personally dont feel the need for spurts and have no desire to pin 3x per day anymore.

if still bbing and if i saw the current pep working i would though.

[ritch]

I hear ya on the pinning frequency... But slin pin shots are so easy! I just carry em in my good ol fanny pack and try to get as many G2 shots a day I can.

I suppose you don't want to hear about the negative aspects of the peptide you're using then, lol... The solution? To use the without dac version, but then we're back to square one, shit...

[ritch]

don't shoot the messenger...

This Article is now out of date. CJC-1295 is counterproductive should not be used because of its effect on GH "bleed".

Partial explanation (Oct 21, 2009)

"Cell-to-cell communication is also likely to reflect the density and proximity of adjacent cells as GH responsiveness (but not sensitivity) to GHRH is enhanced at higher densities and basal GH release is greatest at low densities."

"Cell-to-cell contact may therefore affect the cellular integrity of somatotrophs because GH synthesis or secretory granule storage may be better maintained in high density cell concentration then in low-density concentrations." - Growth Hormone, Stephen Harvey

What happens is cells in the pituitary communicate. They self organize and create a firing network for coordinated growth hormone release. This communication creates a high density of GH releasing cells. They are in close proximity through their communicatory network. The cells have specific spatial relationships that may be modulated by peripheral endocrines. These include sex steroids, thyroid hormones, glucorticoids and even the pancreatic and gut hormones. Their spatial relationship is also effected by physiological state such as nutrient status, age and pregnancy.

As a quick example, corticotroph, thyrotrophs and folliculostellate cells are in close proximity to somatotrophs and communicate with them through gap junctions (almost like just reaching out and touching signaling). They have the potential to effect and be effected by their neighbors.

What happens when you have GHRH always around is you force these somatotrophs to release GH because they are sensitive to the GHRH binding to them and effecting release. By constantly occupying you are preventing them from coordinating with surrounding cell populations. You force these cells to act as low density subpopulations. Basal GH release is greatest when you can disperse the spatial relationship between somatotrophs and that is what an always on GHRH will do.

CJC-1295 as an always on GHRH will force upon somatotrophs loner behavior with a single constant chore. This reduces GH responsiveness as this only occurs when somatotrophs can communicate, self organize and maintain social relationships with the surrounding community. These types of social somatotrophs are better able to make and store GH then the loner cells.

So CJC-1295 seems to disperse somatotrophs and enslave them getting less from them then if it had just let them congregate in towns and cities.

Aging has an effect on the vitality of city centers as well and as we age these somatotroph population centers become less vigorous. By using a more physiological GHRH such as modified GRF(1-29) together with a modulator GHRP-2 we revitalize that inner city and allow our cells to be more social and thus more productive. If instead we choose to use CJC-1295 we not only fail to remedy the problem associated with age , but we may end up exacerbating it.

I conjecture that it also makes them better neighbors to corticotroph, thyrotrophs and folliculostellate cells as well.

[ritch]

last bit of info I would consider if I were you as you're choosing to use just one of the peptides... The info is in bold at the very bottom.


Solution is GHRP + GHRH analog

The solution is simple and highly effective. You administer a GHRH analog with a GHRP. The GHRP creates a pulse of GH. It does this through several mechanisms. One mechanism is the reduction of somatostatin release from the hypothalamus, another is a reduction of somatostatin influence at the pituitary, still another is increased release of GHRH from the brain and finally GHRPs act on the same pituitary cells (somatotrophs) as do GHRHs but use a different mechanism to increase cAMP formation which will further cause GH release from somatotroph stores.

GHRH also has a way of reciprocally reinforcing GHRPs action.

The result is a synergistic GH release.

The GH is not additive it is synergistic. By that I mean:
If GHRH by itself will cause a GH release valued at 2
and GHRP itself will cause a GH release valued at 5

[joe d]

yea it all makes sense. thanks for the posts. in my case its an experiment and i really have nothing to lose so we will see. along with all of the bad i have read a lot of good reviews from users too. we will see.

remember i have nothing and im only looking for a little.

if i produce gh but dont release it this should help. if i dont produce it no peps will help.

[ritch]

would you consider using just ghrp-2 if this does not work out? It has more than twice the gh releasing potential!

[joe d]

would you consider using just ghrp-2 if this does not work out? It has more than twice the gh releasing potential!

no because if i do have gh to be released this will do it to some extent. if i dont it wont do anything and neither will any other gh releaser.

i will consider using other peps if this plan does work. if not ill accept the fact that i need gh and still not buy it with my hrt lol.

[ritch]

^^^ real gh would be optimal for sure...

[joe d]

today march 8th i took my second dose of .5mg. very soon after pinning i got the same swollen face feeling and again blood sugar and vitals where all fine. feeling lasted about 15 mins. hard to say if its helping any. i will finish this vial with 2 more doses then decide where to go with dosage. if im still unsure i will bump to 1mg 2x per week.

[joe d]

im really not sure if this is anything related yet but lately my moods have been slightly better and i seem to have a little more energy. its not much but i notice it. still planning to double the dose at the start of the next bottle and see what that does.