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Thread: Women and Testosterone
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01-07-2010, 09:58 PM #226
GM it would depend on what kind of test and how much but i would tell a BBF to run 50 mg a week for no more than 6 weeks to keep a feminne look ,but all girls a re different,i diffffff,wouldnt recommend 500mg like there was in a recent post.
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01-07-2010, 09:58 PM #227
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01-07-2010, 10:07 PM #228
A typical Test Propioinate cycle is going to be something like 15-25 mg E3D and could run for I suppose 8-10 weeks. Depends on what your purpose is - e.g. off-season or prep. There's really no reason to use Cypionate or Enanthate, primarily because these are the longer esters and if you don't like the sides, you're stuck w/ them for a pretty long time.
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01-07-2010, 10:08 PM #229
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06-02-2010, 11:47 AM #230
Will anyone share a successful cycle they have run? What compounds do you think pros are using?
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06-23-2010, 09:38 PM #231
K. C. Leung, N. Doyle, M. Ballesteros, K. Sjogren, C. K. W. Watts, T. H. Low, G. M. Leong, R. J. M. Ross, and K. K. Y. Ho. Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2. PNAS. February 4, 2003 vol. 100 no. 3 1016-1021.
Abstract
Oral estrogen administration attenuates the metabolic action of growth hormone (GH) in humans. To investigate the mechanism involved, we studied the effects of estrogen on GH signaling through Janus kinase (JAK)2 and the signal transducers and activators of transcription (STATs) in HEK293 cells stably expressing the GH receptor (293GHR), HuH7 (hepatoma) and T-47D (breast cancer) cells. 293GHR cells were transiently transfected with an estrogen receptor-α expression plasmid and luciferase reporters with binding elements for STAT3 and STAT5 or the β-casein promoter. GH stimulated the reporter activities by four- to sixfold. Cotreatment with 17β-estradiol (E2) resulted in a dose-dependent reduction in the response of all three reporters to GH to a maximum of 49–66% of control at 100 nM (P < 0.05). No reduction was seen when E2 was added 1–2 h after GH treatment. Similar inhibitory effects were observed in HuH7 and T-47D cells. E2 suppressed GH-induced JAK2 phosphorylation, an effect attenuated by actinomycin D, suggesting a requirement for gene expression. Next, we investigated the role of the suppressors of cytokine signaling (SOCS) in E2 inhibition. E2 increased the mRNA abundance of SOCS-2 but not SOCS-1 and SOCS-3 in HEK293 cells. The inhibitory effect of E2 was absent in cells lacking SOCS-2 but not in those lacking SOCS-1 and SOCS-3. In conclusion, estrogen inhibits GH signaling, an action mediated by SOCS-2. This paper provides evidence for regulatory interaction between a sex steroid and the GH/JAK/STAT pathway, in which SOCS-2 plays a central mechanistic role.
This is just one of a few studies that found that estrogen impairs the ability of GH to stimulate hepatic IGF-I production because of its negative impact on the growth hormone receptor and signaling. Thus, injecting CJC 1295 or any GHRH by itself will be inhibited in its action on GH release by the sex hormone estrogen in women.
Now does this mean women won't benefit from peptides? Quite the opposite, GHRP's induce a greater GH release response in the somatotrophs in the presence of estrogen than GHRH. Never has it been show that peptides induce acromelagy as has been show in some cases with very high amounts of synthetic hGH. Many of the more masculinizing effects you see in some cases are due to heavy androgen usage combined with hGH.
Hope that clears up things a bit. By the way, very interesting discussion going on. It's about time our women come out and discuss this. Lots can be learned from these discussions as there is very little research on real life situations.
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01-17-2011, 02:05 PM #232
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01-17-2011, 03:17 PM #233
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Anobolics Review makes a cd and book that breaks down all this and explains it to you in a very easy way....check it out.
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05-02-2011, 10:27 AM #234
So the conclusion here is that women and test is an individualized matter. My wife has done var cycles(20mg daily) she has done winny cycles(tabs 20mg daily) and did a prop cycle some 7 years ago. I think the prop was her most successful cycle. Gained a good amount of muscle, strength was phenomenal. But, she was not on a strict diet. Was like a bulk cycle that we should have kept a little cleaner. So now she has steered clear of prop. Im not a big fan of her taking orals daily, I would prefer one to twice a week injects. Save some liver stress and would be easier to stay consistant. Not miss a day here and there. So general opinion.
Right now I have some EQ, some masteron and some test e. Can get prop in matter of days. Not a fan of test e for women with the long half life. The masteron is the one that makes me curious. It is on the lines of a tren, but not as harsh I believe. EQ have seen mixed reviews on here, but it too has a decent half life correct?
39 years old, 5'9" tall 150lbs bout 19%bf. Has a larger build structure wise. Had to go to full D cup last summer to give her a more balanced look. So, she needs to fill out her back and shoulder area. Have some T3 coming this week, she does not like clen. Is presently on 20mg winn dialy, not looking to add to this, looking to replace the winn.
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05-06-2011, 02:29 AM #235
Im pretty new to bodybuilding, looking to compete in my first show this summer. Im natural, but was wondering about test boosters. I won some sups and one is T-Up Black. I dont know anything about this stuff or if women use it and what the effects are. Any info would be much appreciated
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05-06-2011, 06:10 AM #236
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05-06-2011, 08:53 PM #237
I'm not familiar w/ T-Up Black. I checked the label - of course the primary ingredients are some secret mix of stuff. That always makes me wonder because there are well-known t-boosting products out there, as simple as tribulus terrestis or DHEA.
Also given there's so much online about this stuff, I googled "T-Up Black" and "women". Here's some of what I found:
http://www.weightlosssupplement.org/nutrex-t-up-black/ - review says there's nothing in it that actually builds muscle or promotes weightloss. Maybe give you a woody.
http://www.bestslimmingpills.org/nutrex-t-up-black/ - same site / info as the previous one.
Can't find anything else besides the marketing copy on all the sites selling it.
One interesting thing is that most of the "test boosters" out there have a warning that says not for children under 18 (read: males who have not completely developed yet) or women (read: as they don't want to be responsible for anything resulting from a shift in hormone profile). Here is their Warning: Warnings: Absolutley do not use if you are under 18 years of age, pregnant or nursing. Consult your physician before use if you have a medical condition or are taking any presription drugs. Nevre exceed the recommended maximum dosage. KEEP OUT OF REACH OF CHILDREN
Based on this I'd probably guess its ok to use that stuff since its not saying "not for women", and see what it actually does.
For OTC stuff that sounds like it actually works check out this thread on Epistane.
http://forums.rxmuscle.com/showthrea...light=epistane
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05-06-2011, 09:21 PM #238
epi..works well to harden ya up near the end for the ladies...
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05-17-2011, 01:05 PM #239
I disagree with that statement Tat, I think avoid people that have no real experience with dieting and training and supps for women, not just male trainers or husbands, bffs. Honestly it is good to see some women on here with some real knowledge. But in general, I have been around the sport for many years and find most women in the sport are clueless when it comes to supps advice. There are far too many women that workout for like a year or less and lose 20 or 30lbs and suddenly think they are a bber or fitness guru and even get on stage to compete once and then they are handing out advice with no real education. Avoid trainers that do not have your best interests in mind period! Sides from gear usage are largely irreversable. You cannot change that deep voice back, or stop growing that beard ect.. You need to as a female decide on what you are willing to risk and whether it is worth it. Are you gonna make a living of the industry or do you just want to win a show or your Pro Card? Too many women ruin their bodies and then a few years later stop competing.
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05-17-2011, 01:25 PM #240
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