PDA

View Full Version : Winstrol~stanozolol



heavyiron
01-04-2010, 02:28 PM
Winstrol

(http://www.isteroids.com/blog/author/admin/)
Stanozolol, commonly sold under the name Winstrol (oral) and Winstrol Depot (intra-muscular), was developed by Winthrop Laboratories in 1962. It is a synthetic anabolic steroid derived from testosterone, and has been approved by the FDA for human use.

Unlike most injectable anabolic steroids, Stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form. The drug has a large oral bioavailability, due to a C17 α-alkylation which allows the hormone to survive first pass liver metabolism when ingested. It is because of this that Stanozolol is also sold in tablet form.

Stanozolol has been used on both animal and human patients for a number of conditions. In humans, it has been demonstrated to be successful in treating anaemia and hereditary angioedema. Veterinarians may prescribe the drug to improve muscle growth, red blood cell production, increase bone density and stimulate the appetite of debilitated or weakened animals.

Stanozolol is one of the Anabolic steroids commonly used as an ergogenic aid and is banned from use in sports competition under the auspices of the International Association of Athletics Federations (IAAF).

Use in bodybuilding
Like other anabolic steroids, stanolozol is classified as a Schedule III controlled substance under federal regulation. In New York, the state legislature classifies analbolic steroids under DEA Schedule II.

Used illegally in bodybuilding, typically “stacked” with other testosterone-based anabolic steroids, Stanozolol is liked by many due to the fact it causes strength increases without excess weight-gain, promotes increases in vascularity, and will not convert to estrogen. It also does not cause excess water retention, and even sometimes is thought to have a diuretic effect on the body.

Stanozolol is commonly used by athletes and bodybuilders alike to lose fat while retaining lean body mass. It is usually used in a cutting cycle, to help preserve lean body mass while metabolizing adipose, although it has not been proven conclusively that it has any special fat-burning properties.

It is presented most commonly as a 50 mg/mL injection or a 50 mg tablet. However, recently 100 mg/mL versions have become available. A common dosage can be 25-100 mg/day, with optimal results usually seen at 50 mg/day. It is reduced to micrometer particles in aqueous suspension and does not have a typical elimination half-life. Authentic Stanozol can easily be seen, because it will separate in its container if left undisturbed for a number of hours (the micronized crystal will fall to the bottom, and the water suspension will rise to the top). It has a white, milky colour.

It should be taken no more than 48 hours apart, with some users preferring to inject every day, or even twice a day, to maintain serum levels.

The drug has been known to cause masculinising side-effects in women with doses as low as 10 mg per day, and liver damage has been known to occur with extended usage of larger doses.

heavyiron
01-04-2010, 03:03 PM
Stimulation of collagen synthesis by the anabolic steroid stanozolol.

Falanga V (http://forums.rxmuscle.com/pubmed?term=%22Falanga%20V%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Greenberg AS (http://forums.rxmuscle.com/pubmed?term=%22Greenberg%20AS%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Zhou L (http://forums.rxmuscle.com/pubmed?term=%22Zhou%20L%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Ochoa SM (http://forums.rxmuscle.com/pubmed?term=%22Ochoa%20SM%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Roberts AB (http://forums.rxmuscle.com/pubmed?term=%22Roberts%20AB%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Falabella A (http://forums.rxmuscle.com/pubmed?term=%22Falabella%20A%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Yamaguchi Y (http://forums.rxmuscle.com/pubmed?term=%22Yamaguchi%20Y%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract).
University of Miami School of Medicine, Department of Dermatology, Miami Veterans Affairs Medical Center, Florida, USA.

There is evidence that anabolic steroids, which are derived from testosterone and have markedly less androgenic activity, promote tissue growth and enhance tissue repair; however, the mechanisms involved in their anabolic activities remain unclear. In this report, we measured the effect of the anabolic steroid stanozolol on cell replication and collagen synthesis in cultures of adult human dermal fibroblasts. Stanozolol (0.625-5 microg per ml) had no effect on fibroblast replication and cell viability (p = 0.764) but enhanced collagen synthesis (p < 0.01) in a dose-dependent manner (r = 0.907). Stanozolol also increased (by 2-fold) the mRNA levels of alpha1 (I) and alpha1 (III) procollagen and, to a similar extent, upregulated transforming growth factor-beta1 (TGF-beta1) mRNA and peptide levels (p < 0.001). There was no stimulation of collagen synthesis by testosterone. The stimulatory effects of stanozolol on collagen synthesis were blocked by a TGF-beta1 anti-sense oligonucleotide, by antibodies to TGF-beta, and in dermal fibroblast cultures derived from TGF-beta1 knockout mice. We conclude that collagen synthesis is increased by the anabolic steroid stanozolol and that, for the most part, this effect is due to TGF-beta1. These findings point to a novel mechanism of action of anabolic steroids.

PMID: 9856839 [PubMed - indexed for MEDLINE]

heavyiron
01-04-2010, 03:06 PM
The effect of stanozolol on 15nitrogen retention in the dog.

Olson ME (http://forums.rxmuscle.com/pubmed?term=%22Olson%20ME%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Morck DW (http://forums.rxmuscle.com/pubmed?term=%22Morck%20DW%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Quinn KB (http://forums.rxmuscle.com/pubmed?term=%22Quinn%20KB%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract).
Animal Health Unit and Gastrointestinal Sciences, University of Calgary, Alberta. [email protected]

The objective of the study was to determine the influence of either oral or intramuscular administration of stanozolol on nitrogen retention in dogs by using a non-invasive 15N-amino acid tracer technique. Ten healthy, intact, adult male sled dogs received either stanozolol tablets, 2 mg/dog PO, q12h, for 25 days (Group 1, n = 5) or an intramuscular injection of 25 mg of stanozolol on Days 7, 14, 21, and 28 (Group 2, n = 5). A 15N amino acid (5.27 mmol) was infused intravenously into each dog on Day 0 (before stanozolol treatment) and on Day 31 (after stanozolol treatment). Urine was collected by catheterization from each animal 3 times daily for 3 consecutive days. The 15N-urea enrichment in urine was determined by high-resolution mass spectrometry and the total amount of urea in the urine was determined. Both oral and injectable stanozolol resulted in significant (P < 0.05) increases in amino acid nitrogen retention compared to pretreatment values. Oral stanozolol increased nitrogen retention from 29.2 +/- 8.2% to 50.3 +/- 9.2%, while stanozolol injection increased nitrogen retention from 26.6 +/- 9.9% to 67.0 +/- 7.5%. The response to intramuscular administration was significantly greater than the response to the oral dosing regime. Stanozolol increases amino acid nitrogen retention in dogs, as has been previously observed in rats. This action of stanozolol may be beneficial in dogs under stress of surgical trauma and chronic disease.

PMID: 11041505 [PubMed - indexed for MEDLINE]

sassy69
01-15-2010, 03:58 AM
Women & Winstrol
*Note: * caveat about this is general information & not medical recommendations *

Overview
Winstrol, or "winny", is one of the steroids most commonly suggested for women, (along with anavar and primobolan). Winstrol comes in both oral and water-based injectable form (or as water-based, you can actually drink it). It is attractive to women or recommended for women because it is an oral, it has a relatively short half-life and detection time (i.e. it clears the system relatively quickly, reducing the duration of any undesired sides following completion of a cycle), and promotes lean muscle mass without water retention. It is most commonly viewed as a "cutter" for physique competition. Winstrol is also attractive as it tends to be both cheaper and more readily available than anavar or primobolan. Also because of this, it is less likely to be faked.

Winstrol is often grouped with Anavar as good steroid for "beginners" or those who don't want to go into the more aggressive compounds (i.e. injectables), however, it is more androgenic than anavar and sides are less predictable and more unique to the individual, with the potential of being very androgenic. Because of this, anavar would generally be the better recommendation, but winstrol is seen as a viable alternative.

Typical Use
Winstrol is most commonly used both by men and women, as a cutter during competition prep. It promotes lean, hard muscle mass without water retention. One might see figure competitors running a winstrol-only cycle, or a more advanced physique competitor using it in a stack towards the final weeks of a competition prep. It might also be used, especially in oral form, by someone who wants to "take it to the next level".

Typical Cycle
Oral winstrol: can be cycled similarly to anavar, as they both have comparable half-lives and detection times and doses.
Dose: 5-15 mg / day - split the dose 1/2 in the AM, 1/2 in the PM
Duration: 8-12 weeks
Injectable winstrol:
Dose: 25 mg E3D
Duration: 8-12 weeks
No taper down or post cycle therapy (PCT) is needed.
If chosen to include in a competition cutting stack, schedule towards the final weeks of prep. It takes about 2 weeks to "show itself".

Typical Sides
- interrupted period / flow - may take a few months for the flow to come back as normal.
- may still experience usual menstrual sides (cramps, bloating, etc.) on your regular menstrual schedule
- mild to aggressive acne
- oily skin / hair
- hairloss
- scratchy throat / cracky or deepening voice
- dry joints

n8te
02-10-2010, 10:07 PM
Are these dosages the same for men as women?

sassy69
06-29-2010, 11:59 AM
Are these dosages the same for men as women?


No. Since testosterone is the primary male hormone, the amounts used can be an order of magnitude higher than for women. Also because women don't need to worry about an exogenous test source shutting down their natural test production, women can run the cycle much longer, though at much lower doses, and not require PCT at the end of it.

Across the board you cannot compare men's and women's doses of AAS.

barbellman
12-13-2010, 04:38 PM
Winny is awesome, love it, benched 500 raw my first time on winny. Take your joint supps though :yep:

D_T
12-29-2010, 11:40 PM
Gonna try Test/Deca/Winny/GH next strength phase.

barbellman
01-03-2011, 09:49 PM
Gonna try Test/Deca/Winny/GH next strength phase.


That should acutally be pretty badass, I'm not the only one who responds to it by getting freaky strong. My buddy was hitting 315 for 5x bench press, after 6 weeks of winny 50mg + 500mg test He benched 435 for 4, I was shocked

Bolan
01-04-2011, 12:25 PM
Winny is awesome, love it, benched 500 raw my first time on winny. Take your joint supps though :yep:

Great stuff.... Can be used in a bulker to harden up gains, and of course pre-contest for that granite look. Definately run a bit of NPP or Deca with it or OUCH.

daft205
01-04-2011, 01:07 PM
Great profile Heavy, thanks!

D_T
01-05-2011, 05:25 PM
The knots get to me after a while; also get lethargic sometimes.

heavyiron
05-07-2011, 05:45 PM
Winstrol (Stanozolol) A Basic Guide By Heavyiron

Stanozolol has a anabolic rating of 320 and an androgenic rating of 30 making it an excellent steroid for promoting muscle growth with zero water retention. Stanozolol cannot aromatize into estrogen so estrogenic side effects like water retention are not a factor. Even the most gyno prone users can use Winstrol without any worry of gynocomastia.

Winstrol is excellent for dieting bodybuilders and is best employed near the end of a cutting cycle to keep the user anabolic but give a dry shredded appearance. Winstrol is also favored by speed athletes like runners, swimmers and even fighters who want to stay in a certain weight class but want to have an anabolic edge.

Winstrol also significantly lowers SHBG even at very low doses in a matter of a few days. This is significant because that equates to more free testosterone. Winstrol stacked with testosterone means more testosterone stays free or active. Some users report increased sex drive when stacking Winstrol with testosterone. Basically Winstrol makes your testosterone work better and it can raise libido.

Administration Men

A good starting dose for performance is 25-50mg Winstrol daily. I prefer to stack Winstrol with Testosterone Propionate. I also prefer shorter runs of around 3-6 weeks due to liver stress and Winstrol’s profound ability to lower HDL and raise LDL like most orals.

Administration Women

A good starting dose for performance is 10mg Winstrol daily for 6-8 weeks. A more adventuresome female may take up to 20mg daily however side effects will increase with dosage.

Not all Winstrol is created equal

Injectable Winstrol is a suspension as opposed to a solution. Suspensions have tiny particles that are visible with the naked eye. If left on the shelf for a few days many times the particles will sink to the bottom leaving the clear solvents and water on the top. Depending on the manufacturer, particle sizes vary meaning some Winstrol preparations can clog a 22 gauge needle. Ultra micronized Winstrol can easily pass through a 25 gauge needle making injections more comfortable.

http://forums.musculardevelopment.com/attachment.php?attachmentid=241401&d=1304735341

Can I mix water based Winstrol with oil based steroids?

A common misconception is that oil and water based steroids cannot be injected together. This is absolutely false. You may mix water based Winstrol with any oil based steroid. The picture below is Cypionate and Winstrol together in the same syringe (Winny lava lamp).

http://forums.musculardevelopment.com/attachment.php?attachmentid=241399&d=1304734852

Bacteria and water based steroids (drinking your Winstrol)

Bacteria have an easier time living in water based steroids than in oil based steroids. Winstrol is notorious for causing painful lumps at the injection site and for causing infections and or abscesses. This is because many underground labs improperly assemble steroids not because of the Winstrol itself. I don't recommend injecting UGL Winstrol due to the risk for infection unless it's a regulated lab. I only recommend human grade injectable Winstrol made at GMP standards.

Do you know what you are injecting when using an under ground lab? (Graphic Video) - RX Muscle Forums


Because injectable Winstrol can be ingested orally and because it can cause infections when injected some users drink their injectable Winstrol to avoid infections as gastric acid destroys the bacteria. You may drink your Winstrol however injecting has been proven to work better mg for mg than oral administration. Although, injectable Winstrol tastes absolutely awful.

Overall Winstrol is an excellent cutting anabolic and also well suited for speed sports. It’s the “summer” steroid because it does not promote the watery look that so many other steroids do.

http://forums.musculardevelopment.com/attachment.php?attachmentid=241398&d=1304734543

~heavyiron

JohnnyStyles
05-07-2011, 07:11 PM
Nice info....I'll prolly stack clen with it....later on this year....Keep this up....

BTW Sassy...owning it!!! xoxo

adpolice
05-07-2011, 10:28 PM
Luckily i can find real desmas,otherwise i would never inject ugl water based steroids

daywalker72
05-08-2011, 02:18 PM
have any of you included this in a bulk cycle? if so what were the results like? ive used it for contest prep with some test and loved it.