View Full Version : (17alpha methyl-17beta-hydroxy-androst-1-ene-3-one

01-04-2010, 04:10 PM
Methyl-1-testosterone (methyldihydroboldenone)

Androgenic 100-220
Anabolic 910-1,600
Standard Methyltestosterone (oral)
Chemical Name 17alpha methyl-17beta-hydroxyandrost-1-ene-3-one
Estrogenic Activity none
Progestational Activity moderate

Methyl-1-testosterone (methyldihydroboldenone) is an oral anabolic steroid derived from dihydrotestosterone.lt is closest in structure to 1-testosterone (dihydroboldenone), differing only by the addition of c-17 alkylation (which does change the activity of this steroid considerably). M1T for short, this agent can be looked at as some kind of amalgamation of Primobolan, Winstrol, and trenbolone. It has the basic 1-ene structure of Primobolan, the bioavailability of a methylated oral steroid like Winstrol, and the high potency of a strong synthetic anabolic and androgenic agent like trenbolone. Based on standard assays, the potency of methyl-1-testosterone actually exceeds that of every prescription anabolic steroid currently sold. It is popular among bodybuilders as a bulking agent, with an ability to promote rapid gains in muscle size and strength, which are often accompanied by some level of water or fat retention.

Methyl-1-testosterone was first described in 1962.This compound was developed during some of the most active years of steroid research, a time when literally hundreds of different effective anabolic agents were being actively studied and pursued by drug companies. Although methyl-1-testosterone did see some favorable assays, displaying a high level of potency and an acceptable ratio of anabolic to androgenic effect, like most agents synthesized during this time period it never actually developed into a medicine. As is common in many areas of pharmaceutical research, a select number of agents were given the dollars for full studies and eventual release, and the rest were" ignored. Methyl-1-testosteroe, for whatever reason, was simply not one of the select few drugs to reach pharmacy shelves, and it lay dormant in the medical books for approximately forty years.
Methyl-1-testosterone reemerged sharply in 2003, when it was introduced as an OTC (Over-The-Counter) "nutritional supplement"in the United States, due to the fact that it was unknown when the 1991 law controlling anabolic steroids was written, and therefore not included. The product was introduced to the market by Legal Gear, and was soon extremely popular due to its very high level of effectiveness. It was also soon the subject of many generic copies. Methyl-1-testosterone did not last long in the U.S., and laws were soon passed to include it as a controlled substance. The laws went into effect January 20, 2005, at which point the possession or distribution of this steroid started carrying the same Federal penalties as other anabolic steroids. This effectively ended the market for methyl-1-testosterone, and the agent is again unavailable to bodybuilders worldwide.

How Supplied:
No prescription drug product containing methyl-1testosterone currently exists. When it was sold as an OTC supplement, it was produced as an oral capsule and tablet in various strengths.
Structural Characteristics:
Methyl-1-Testosterone is a derivative of dihydrotestosterone.lt contains 1) the addition of a methyl group at carbon 17-alpha to protect the hormone during oral administration and 2) the introduction of a double bond between carbons 1 and 2, which helps to stabilize the 3-keto group and increase the steroid's anabolic properties.

Administration (General):
Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract. For maximum utilization, this steroid should be taken on an empty stomach.
Administration (Men):
Methyl-l-Testosterone was never approved for use in humans. Prescribing guidelines are unavailable. For physique-or performance-enhancing purposes, a typical effective oral daily dose will be in the range of 5-10 mg, taken for no longer than 4-6 weeks. A dose of 20 mg is sometimes used, although this increases the likelihood for side effects. Many users feel they are better served by not exceeding a 10 mg daily dose, and instead stack it with an injectable like testosterone cypionate (200-400 mg per week) when a stronger effect is needed. This may reduce liver toxicity compared to a higher dose of M1T, and also provide a more balanced cycle in terms of anabolic vs. androgenic effect. A common complaint when M1T is taken alone is lethargy, which may be due, in part, to its low androgenic or estrogenic component. Stacking it with an aromatizable androgen like testosterone will usually alleviate this problem. Note that while a small percentage of users exceed 20 mg per day, it should be remembered that even this is a serious dose for a potent steroid like this, and is not to be taken lightly, either for its effectiveness or toxicity. Like Anadrol, methyl-ltestosterone is not necessarily a friendly steroid, but it is definitely an effective one.
Administration (Women):
Methyl-l-Testosterone was never approved for use in humans. Prescribing guidelines are unavailable.This agent is not recommended for women for physique-or performance-enhancing purposes due to its high potency and tendency to produce virilizing side effects.

Llewellyn’s W. (2009). Anabolics (9th ed), Methyl-1-testosterone methyldihydroboldenone(pp. 299-301): Jupiter, FL: Molecular Nutrition